Compaction Behavior of Isomalt after Roll Compaction
نویسندگان
چکیده
منابع مشابه
Compaction Behavior of Isomalt after Roll Compaction
The suitability of the new isomalt grade galenIQ™ 801 for dry granulation and following tableting is evaluated in this study. Isomalt alone, as well as a blend of equal parts with dibasic calcium phosphate, is roll compacted and tableted. Particle size distribution and flowability of the granules and friability and disintegration time of the tablets are determined. Tensile strength of tab...
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Six mixtures, containing 10, 20 and 30% w/w ibuprofen and isomalt, were compacted by a traditional or ultrasound-assisted machine and analysed by means of thermal (DSC and TGA) and micro-spectrometry (Raman and FT-IR) techniques. Ultrasound discharge causes melting of ibuprofen powder, transforming into a paste that could not assume the shape of a tablet; when in mixture with isomalt, thermal e...
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H. Mangal , M. Kirsolak , B. Ehlig , P. Kleinebudde 1 1 Heinrich Heine University, 2 Nisso Chemical Europe GmbH Purpose Tablets produced from granules, which were obtained by roll compaction/dry granulation show reduced tensile strength compared to tablets produced by direct compression or after wet granulation. This emphasizes the importance of binders for this application besides their genera...
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Compaction is a mechanical process in which an earthen material is made more dense. The densification occurs as a direct result of the mechanical loading, and is essentially complete at the end of the loading. Volume changes are incurred as a result of a reduction in the quantity of air voids— water content remaining constant. Since it is impractical to squeeze out all the air, the as-compacted...
متن کاملOn the Compaction and Viscous Behavior of Deep-Water Reservoirs
There have been many studies on reservoir compaction where different mechanisms being suggested as the reasons behind the integrity of unconsolidated reservoirs during production. Theory of poroelasticity is often used to evaluate the likelihood of compaction under these circumstances, but it is often failed to explain the creep behavior of unconsolidated formations. In this study, attempts are...
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ژورنال
عنوان ژورنال: Pharmaceutics
سال: 2012
ISSN: 1999-4923
DOI: 10.3390/pharmaceutics4040494